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Posts Tagged ‘glucosamine’

Glucosamine and Chondroitin

Glucosamine and Chondroitin


A joint health supplement is a safe and inexpensive treatment for arthritis.  Glucosamine has been used for twenty years to help with joint pain.  Nutramax is the manufacturer of CosaminDS and other glucosamine and chondroitin based joint health supplements.

The joint health supplement industry is not regulated.  That means companies can basically design and engineer their products however they see fit.  Nutramax follows pharmaceutical guidelines at their facility.  That means they produce, package, and ship their glucosamine products following the same regulations that drug companies must obey.

Nutramax has been in business since 1992.  They were the first company to market and sell glucosamine to treat osteoarthritis.  You now why they are still in business and growing?  The answer is simple.  Their products work.

Glucosamine for Arthritis

Glucosamine for Arthritis

Glucosamine is a “building block” molecule that your body produces naturally.  Glucosamine is essential in the production of proteins important to joint health.

Glucosamine stimulates the production of cartilage.  In young healthy bodies cartilage cells reproduce and protect themselves.  As we age cartilage cells die and are not replaced.  Glucosamine helps stop the break-down of cartilage and reduce knee pain.

Glucosamine can be obtained over the counter and is a safe joint health supplement.



Glucosamine is an amino sugar or building block molecule produced by the body for the production of structures important to cartilage and joint health. These structures are called proteoglycans. Glucosamine helps proteoglycans.

Taken orally, supplemental glucosamine can reduce pain, improve function, and enhance quality of life in as little as eight weeks.  It can absolutely help your knee osteoarthritis.

People have been taking Glucosamine safely for over 20 years. Clinical studies since the early 1980s consistently report that glucosamine is safe. However there are a few considerations:

  • Glucosamine is usually derived from shellfish.  Those allergic should avoid it.
  • Diabetics can experience changes in their insulin levels with glucosamine, even though the body cannot convert glucosamine into glucose.  In diabetics many factors can lead to fluctuations with insulin levels, so it important to check with your doctor before taking the joint health supplement.
  • Pregnant women should avoid glucosamine.



A chondrocyte is a cell found within cartilage.  Chondrocytes are like small factories that produce collagen and proteoglycans – the main ingredients in the cartilaginous matrix.

Collagen is a thin, ropey protein that is the primary component of connective tissue.

Proteoglycans fill in the spaces between the collagen cells.  Glucosamine and chondroitin help strengthen the cartilaginous matrix and help control knee osteoarthritis on the cellular level.

There are alternatives to taking medication for osteoarthritis. While there is no cure for osteoarthritis, many of the treatments we will briefly describe have been successful for people living with this degenerative condition. The first osteoarthritis treatment you may want to try is hot and cold therapy. Placing a hot compress to your joints will increase blood flow to the region and soothe inflammation. Applying a cold compress has a numbing effect on nerves that are sensitive to pain.

Another osteoarthritis treatment to try is a lifestyle change. Try changing your eating habits and kicking bad habits like smoking and drinking excessively. Increasing exercise will also help increase blood flow to your joints. Weight loss will also alleviate pressure on your joints since heavy people tend to stress their joints out faster than people in healthy weight ranges. These relatively minor, unobtrusive treatments can have a significant impact on the pain associated with osteoarthritis.

Avoca ASU

Avoca ASU

Avoca ASU from Nutramax is a joint health supplement that contains non-shellfish glucosamine, NMX1000 avocado/soybean unsaponifiables (ASU), and methylsulfonylmethane (MSM).  It also has decaffeinated green tea for antioxidant health benefits.  All ingredients are from non-animal origin.

So vegetarians and those allergic to shellfish now have a new treatment option for their knee osteoarthritis.  If you couldn’t take Cosamin DS – try Avoca ASU.

Cosamin ASU

Cosamin ASU

CosaminDS has been the premium joint health supplement on the market for over ten years.  Nutramax has discovered a method of making their original product more effective.  Cosamin ASU is maximum strength glucosamine and chondroitin.

This new formula from Nutramax is trademarked and shown in cell studies to be better than the combination of glucosamine and chondroitin sulfate at inhibiting several agents involved in cartilage breakdown.

If Cosamin DS helped with your knee osteoarthritis then this product can take your pain relief to an entire new level.

Cosamin DS

Cosamin DS

Cosamin DS is the only brand of glucosamine and chondroitin proven effective in published U.S. studies.  The studies show that joint pain is reduced.

Cosamin DS, designed and manufactured by Nutramax Labs, contains the full clinical strength of glucosamine and chondroitin.  Nutramax Labs manufacture this joint health supplement as if it were a pharmaceutical – meeting rigorous production and safety protocols.

Thousands of patients have successfully used Cosamin DS to treat their osteoarthritis of the knee.



This blog post is a continuation of a series of articles from the American Academy of Orthopedic Surgeons’ (AAOS) Full Guideline for the Treatment of Osteoarthritis.

Recommendation 12 – The AAOS recommends that glucosamine and/or chondroitin sulfate or hydrochloride not be prescribed for patients with symptomatic osteoarthritis of the knee.

This recommendation was based on a report from the Agency for Healthcare Research and Quality.  The report was based on one random controlled trial and six systematic reviews on the use of chondroitin sulfate, and/or glucosamine, or hydrochloride among patients with osteoarthritis of the knee.

The random controlled trial found that glucosamine and/or chondroitin did not have any clinical benefit, though five of the six systematic reviews concluded that glucosamine and/or chondroitin are superior to placebo.

Since the Random Controlled Trial is stronger science than the systematic reviews, the AAOS based their decision on the one study.

This is a continuation of our series on the Osteoarthritis Research Society International (OARSI) recommendations for the management of hip and knee osteoarthritis published in the Journal of Osteoarthritis and Cartilage.

glucosamine and chondrotin

Recommendation XIX

In patients with symptomatic knee OA glucosamine sulphate and chondrotin sulphate may have structure-modifying effects.

Two randomized controlled trials involving 414 patients reported evidence that 1500mg of glucosamine sulphate taken on a daily basis may have structure-modifying effects in patients with knee OA.  This means cartilage may be rebuilt.

The research team gave this osteoarthritis treatment option a Strength of Recommendation score of 41%.

W. Zhang Ph.D., Moskowitz M.D., et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis and Cartilage. (2008) 16, 137-162.