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NSAIDs – How do they work?

November 21, 2010
NSAIDs

NSAIDs

Non-steroidal anti inflammatory drugs (NSAIDs) relieve the pain associated with knee osteoarthritis on a chemical level.

Enzymes called Cox-1 and Cox-2 are a contributing factor in the creation of prostaglandins. ┬áProstaglandins are responsible for swelling and the sensation of pain. ┬áNSAID’s block Cox enzymes, so your body does not produce as many prostaglandins.

So NSAID’s reduce pain and swelling by blocking Cox-1 and Cox-2 enzymes, thus your body doesn’t produce as many prostaglandins, and pain and swelling is reduced.



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