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OARSI – Recommendation XIII: Use caution with acetaminophen

July 25, 2010

This is a continuation of our series on the Osteoarthritis Research Society International (OARSI) recommendations for the management of hip and knee osteoarthritis published in the Journal of Osteoarthritis and Cartilage.

acetaminophen

acetaminophen

Recommendation XIII

Acetaminophen or paracetamol can be an effective oral pain reliever for treatment of mild to moderate hip and knee osteoarthritis.

16 out of 16 guidelines examined by the research team recommend acetaminophen as a pain reliever.  Doses up to 4 grams per day is usually a first choice for mild to moderate pain relief.  However the safety and efficacy of long-term use can be dangerous.

The research team gave this osteoarthritis treatment option a Strength of Recommendation score of 92%.

W. Zhang Ph.D., Moskowitz M.D., et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis and Cartilage. (2008) 16, 137-162.


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