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Archive for the ‘Glucosamine’ Category

Cosamin DS

Cosamin DS

Cosamin DS is the only brand of glucosamine and chondroitin proven effective in published U.S. studies.  The studies show that joint pain is reduced.

Cosamin DS, designed and manufactured by Nutramax Labs, contains the full clinical strength of glucosamine and chondroitin.  Nutramax Labs manufacture this joint health supplement as if it were a pharmaceutical – meeting rigorous production and safety protocols.

Thousands of patients have successfully used Cosamin DS to treat their osteoarthritis of the knee.




This is a continuation of our series on the Osteoarthritis Research Society International (OARSI) recommendations for the management of hip and knee osteoarthritis published in the Journal of Osteoarthritis and Cartilage.

glucosamine and chondrotin

Recommendation XIX

In patients with symptomatic knee OA glucosamine sulphate and chondrotin sulphate may have structure-modifying effects.

Two randomized controlled trials involving 414 patients reported evidence that 1500mg of glucosamine sulphate taken on a daily basis may have structure-modifying effects in patients with knee OA.  This means cartilage may be rebuilt.

The research team gave this osteoarthritis treatment option a Strength of Recommendation score of 41%.

W. Zhang Ph.D., Moskowitz M.D., et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis and Cartilage. (2008) 16, 137-162.




This is a continuation of our series on the Osteoarthritis Research Society International (OARSI) recommendations for the management of hip and knee osteoarthritis published in the Journal of Osteoarthritis and Cartilage.

glucosamine and chondroitin

Recommendation XVIII

Glucosamine and Chondroitin sulphate may be effective in providing symptomatic pain relief in patients with knee osteoarthritis.

Analysis of eight randomized controlled trials involving 755 patients reported moderate pain reduction.  However with so many products on the market with varying purity levels of glucosamine and chondroitin there is significant controversy as to the efficacy of this treatment option for knee osteoarthritis.

No adverse effects are reported from long-term use of glucosamine and chondroitin.  However if no response is apparent within 6 months treatment should be discontinued.

The research team gave this osteoarthritis treatment option a Strength of Recommendation score of 63%.

W. Zhang Ph.D., Moskowitz M.D., et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis and Cartilage. (2008) 16, 137-162.


Since first being extracted and purified in the 1960s, chondroitin sulfate has been used to combat the debilitating affects of osteoarthritis. The compound is found in various animal cartilage and bovine tracheas, and it is created through synthetic means as well. Chondroitin sulfate is often paired with glucosamine to create drugs intended to improve, and possibly reverse, osteoarthritis.

A typical dose of chondroitin sulfate is between 800 and 1,200 mg per day. Several studies have confirmed that chondroitin sulfate is effective at decreasing the pain and remedying the functional shortcomings that osteoarthritis creates. However, the Mayo Clinic suggests that it may take several weeks for patients to recognize the full benefits of the compound.