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Archive for the ‘Drugs’ Category

Celebrex

Celebrex

116,00 patients takings non steroidal anti inflammatory drugs (NSAIDs) were studied by The British Journal of Medicine.  This recent publication states that taking certain medications, like celecoxib, will increase the risk of cardiovascular events in patients, especially as the dosage increases.  Celecoxib is sold as Celebrex by the pharmaceutical giant Pfizer.

Pfizer is the world’s largest drug maker.  In 2004 Pfizer spent $117 Million in advertising Celebrex.  In 2005 the FDA forced a moratorium on Pfizer’s advertising efforts of Celebrex because of the cardiovascular risks.  Sales of Celebrex plummeted by $1.7 BILLION.  Four months later the advertising ban was lifted.

Now Pfizer must print that “Celebrex may increase the chance of a heart attack or stroke that can lead to death” on every box sold.   Consumer groups have launched campaigns in magazines that Pfizer should be forced to stop selling Celebrex, not encouraging people to use it.

So why have you never heard of treating knee osteoarthritis with a knee brace?  Because the companies that manufacture them are small.  They cannot compete with big pharma.  Pfizer spent $117 million on advertising one single drug in 2004.  The companies that manufacture braces to treat osteoarthritis measure their advertising budgets in the tens of thousands.  Billions and billions of dollars are spent annually to treat osteoarthritis.  Half of one percent of that money is spent on bracing.

Talk to your doctor, do your homework, and try conservative treatments for your knee OA.  There are much safer options than drugs.  NSAIDs kill.  Knee braces do not.



Ibuprofen

Ibuprofen

A new study released by the British Journal of Medicine reports that of all the non steroidal anti inflammatory drugs, Ibuprofen carries the highest risk of stroke.

The researchers used a sophisticated system to examine studies and trials that included over 116,000 patients.  Research was examined that compared NSAIDs with other NSAIDs and placebos.

This large meta-analysis discovered compelling cardiovascular problems in patients using prescription-strength NSAIDs.  Dr. Jeffrey Berger of NYU Medical Center in Manhattan said that a patient can take enough pills purchased over the counter to equal a prescription dose, so the findings “most likely” apply to over-the-counter NSAIDs as well as prescription-strength.

So check with your doctor.  Stop looking in your medicine cabinet for pain relief the next time your knee is hurting.  A knee brace is a safe, conservative treatment option for your osteoarthritis.  Nobody has ever died from a knee brace.



NSAIDs

NSAIDs

Non-steroidal anti inflammatory drugs (NSAIDs) relieve the pain associated with knee osteoarthritis on a chemical level.

Enzymes called Cox-1 and Cox-2 are a contributing factor in the creation of prostaglandins.  Prostaglandins are responsible for swelling and the sensation of pain.  NSAID’s block Cox enzymes, so your body does not produce as many prostaglandins.

So NSAID’s reduce pain and swelling by blocking Cox-1 and Cox-2 enzymes, thus your body doesn’t produce as many prostaglandins, and pain and swelling is reduced.



Attention!

Attention!

NSAIDs are commonly prescribed and recommended to treat the pain associated with osteoarthritis of the knee.  This series of posts is about the side effects associated with nonsteroidal anti-inflammatory drugs.  Some of the problems that these medications cause are very serious and can adversely effect your health much worse than the pain in your knee caused by OA.

  • Liver Failure
  • Kidney Failure
  • Heart Attack
  • Stroke
  • Death

NSAID use has been linked to all of the above conditions.  It is important you talk to your doctor and know all of the risks associated with any medication you take.  With NSAIDs, know all of the precautions you must take to safely treat your knee pain.

Think about a conservative treatment option for your knee OA.  Nobody has ever died from wearing a knee brace.



Clotting Problems

Clotting Problems

NSAID use can interfere with the clotting of blood.  This series of blog posts is about the possible side effects associated with non-steroidal anti-inflammatory drugs used to treat knee osteoarthritis.

If the efficiency of your body’s ability to clot blood is affected you may bruise easily or have trouble stopping bleeding if you are cut or lacerated.

A study published in the Journal of Bone and Joint Surgery concluded that neoprene knee sleeves can reduce pain and increase function in a knee with osteoarthritis more effectively than NSAIDs.



Fluid Retention

Fluid Retention

Observable swelling from fluid retention in the tissues of your body is called edema.  Edema is a possible side effect from using nonsteroidal anti-inflammatory drugs to treat the osteoarthritis in your knee.  The swelling is most common in the feet and ankles.

Swollen ankles can also be a symptom of heart, kidney, and respiratory problems.  Edema can be the sign of a serious medical condition.  Since NSAID use can also result in serious heart, kidney, and respiratory problems, consult your physician immediately is your ankles swell unexpectedly.



Changes in Vision

Changes in Vision

Using NSAIDs to treat the pain associated with osteoarthritis of the knee can lead to changes in your vision.  Some of the more commonly reported vision problems are:

  • Double Vision
  • Color Perception Irregularities
  • Night Blindness
  • Decreased Vision
  • Eye Pain
  • Eye Irritation
  • Blindness

That’s an awful lot to worry about.  Why not try a joint health supplement?  The worst side-effect of Cosamin DS is gas.



Tinnitus

Tinnitus

Knee osteoarthritis is often treated with nonsteroidal anti-inflammatory drugs.  NSAIDs can have some potentially serious side effects.  Tinnitus is one of those possible side effects.

Tinnitus – this is not a disease but an aural condition.  It is characterized by noises in your head when everything is quiet.  Tinnitus is usually worse at night or when in very quiet places.  The noises can occur in one or both ears and can sound like buzzing whistling, ringing, or hissing.



Itching

Itching

Allergic Reactions are a known and well-documented side effect associated with NSAIDs used to treat OA of the knee.  Nonsteroidal anti-inflammatory drugs are often recommended and prescribed to reduce the pain and swelling associated with knee osteoarthritis.  Symptoms of an allergic reaction may include:

  • Rash
  • Itching
  • Swelling
  • Dizziness
  • Shortness of Breath

Your physician should be contacted immediately if you notice any of the following symptoms.  If you have trouble breathing call 911.



Fatigue

Fatigue

Nonsteroidal Anti-inflammatory Drugs are often used to treat osteoarthritis of the knee.  However these medications are associated with a host of side effects.  This series of blog posts examines these side effects.

NSAID use can lead to fatigue and drowsiness.  Fatigue is different than drowsiness.  Drowsiness is the need to sleep.  Fatigue is a lack of energy and/or motivation.  This encompasses both physical and mental conditions.  It should be left up to a physician to distinguish between the two.